
Podcast by Paradigm Productions

Podcast by Paradigm Productions

19 June 2026
The first in person video recording of a Paradigm Shock episode, now available on the new YouTube Channel.
In a thought-provoking discussion on Paradigm Shock, University of Notre Dame Professor Dr. Joanna Santos explores the significant intersection of AI and cybersecurity. The episode sheds light on the capabilities of Anthropic's Mythos and other advanced models, an AI that can identify and patch vulnerabilities autonomously but is kept under wraps to prevent misuse. Santos emphasizes the shifting dynamics in cyber threats, as AI speeds up the detection and exploitation race. She also touches on the potential role of quantum computing in cybersecurity and the remarkable journey that has brought her to the forefront of this rapidly evolving field. They finish with thoughts on the World Cup
Note:Recorded on June 4th 2026
YouTube Recording: https://www.youtube.com/watch?v=d10n0oFnlE8&t=378s
Connect
Joanna Santos GitHub page: https://joannacss.github.io/
Notre Dame Page: https://engineering.nd.edu/faculty/joanna-cecilia-da-silva-santos/
Google Scholar Page: https://scholar.google.ca/citations?user=mkGmYyAAAAAJ&hl=en&oi=sra
Notre Dame S2E Lab: https://s2e-lab.github.io/members/
Subscribe to Paradigm Shock on YouTube: / @paradigmshock2000 Show
Contact Show Parshock2025@gmail.com
00:00
58:46

20 May 2026
Charlie Bullock from The Institute for Law and AI joins Anjon Roy on Paradigm Shock to delve into the challenges of AI governance amidst high uncertainty. Highlighting the radical optionality framework, Bullock advocates for developing government capabilities to respond flexibly to AI advancements. They explore policy suggestions like transparency laws and evaluation mechanisms as crucial tools for managing AI's rapid progression. By prioritizing institutional readiness over fixed regulations, the dialogue points to a necessary shift in political focus to adequately prepare for AI's potentially revolutionary impacts on society, even when the exact outcomes remain unpredictable.
Show Links
Radical Optionality Paper: https://law-ai.org/radical-optionality/
Charlie Bullock LinkedIn: https://www.linkedin.com/in/charlie-bullock-79169b168/
Ad Link
Registration Link for Pause AI - Oxford Style Debate in Chicago on June 10th
https://luma.com/ais-chicago
Contact Show
00:00
01:03:22

15 May 2026
The latest episode of Paradigm Shock features Anjon interviewing Stephen Saine, CEO of AnyBio, discussing the hurdles of deploying AI in clinical settings. Saine explains how AnyBio simplifies compliance for healthcare developers, making it easier to bring AI innovations to market securely. He describes the challenges of maintaining data safety with personal health information and the regulatory landscape surrounding AI in healthcare. The conversation covers the risks and opportunities of "vibe coding" and the potential risks of hallucination in clinical AI, stressing the critical importance of compliance to successfully integrate AI into healthcare solutions safely and effectively.
Show Links
AnyBio Webpage: https://anybio.io/
Stephen’s LinkedIn: https://www.linkedin.com/in/stephensaine/
Contact Show
00:00
33:02

27 April 2026
(Note: This episode is sponsored by Edel Finance)
In this episode of Paradigm Shock, host Anjon Roy speaks with Andrés Soltermann from Edel Finance about their groundbreaking work in decentralized finance. Sulterman discusses his journey from software engineering to co-founding Edel, a company focused on creating a lending market for tokenized equities. They explore the transformative potential of blockchain technology in securities lending and the broader financial infrastructure, highlighting how Edel Finance is pioneering new opportunities in the space. As they delve into the company's motivations and strategic decisions, listeners gain insight into the evolving landscape of fintech and blockchain.
Show Links
Edel Finance Webpage: https://www.edel.finance/
Contact Show
New YouTube Channel!
https://youtu.be/NNSf-V24PdM
00:00
52:37

02 April 2026
Anjon Roy welcomes AI Governance expert Andrew Harrison to Paradigm Shock to discuss the complex challenges of AI Safety and Governance. Harrison shares insights from his multidisciplinary educational and professional journey, emphasizing the importance of synthesizing perspectives from psychology, data science, technology and international relations. The discussion spans emerging risks associated with the wide distribution of agent deployment, model scheming, technical solutions like mechanistic interpretability, the pivotal role of constitutional AI frameworks, and cyber risks from potential uplift scenarios. The episode underscores the transformative potential and risks of AI and the necessity of understanding its impacts on economic systems, international relations, and organizational dynamics. Harrison calls for a nuanced understanding of emergent risks, advocating for a balanced approach that draws from both technical and policy-driven perspectives to address AI's potential and perils.
Links
Andrew’s LinkedIn: https://www.linkedin.com/in/andrewphilipharrison/
BlueDot Impact AGI Course: https://bluedot.org/courses/agi-strategy
Contact Show
New Substack- https://aiuncertainty.substack.com/
00:00
01:07:58

26 March 2026
In the Paradigm Shock podcast, Anjon Roy and guest David Timis delve into the complex dynamics of AI's impact on the labor market. As a leading advocate in workforce development, Timis shares insights from his roles across various global organizations. They tackle critical questions about AI's potential to either diminish or redistribute employment opportunities. Highlighting both theoretical debates and on-ground realities, the discussion focuses on the current and future effects of AI on job availability, particularly for vulnerable communities and younger workers entering the job market. They also discuss potential catastrophic risk scenarios, such as the extreme power concentration that could result from mass labor displacement, and the potential limits of Jevons Paradox.
Show Notes
David’s website: https://www.davidtimis.com/
LinkedIn: https://www.linkedin.com/in/davidtimis/
David’s WEF Page: https://www.weforum.org/stories/authors/david-timis/
Concepts discussed:
https://davidoks.blog/p/why-the-atm-didnt-kill-bank-teller
https://stayathomemacro.substack.com/p/a-year-with-no-jobsbut-no-recession
https://www.youtube.com/shorts/VhTO6HGkS-k
Contact Show
New Substack- https://aiuncertainty.substack.com/
00:00
01:01:13